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Q: BP Meds & Dialysis
How can we know for sure how much of my wifes meds are being dialized
out during dialysis. 10 mg zyprexa 2000 mg depakote 50 mg lamictal 150 mg
of effexor xr. she is now depressed and seeing our Dr. in the morning. she was
hospitalized at Emory in Atlanta for 29 days then home for 2 weeks then back in
for 5 days. On dialysis for 3 months. Any words will be helpful.
Dear Mr. B' --
The dialysis doc' should be able to answer that question. Let's see if I can
find anything in the literature that might help you. There is a book about
changing drug dosing for people with kidney problems by Aranoff and colleagues
called Drug Prescribing in Renal Failure (here's the
Amazon link); they make available their drug tables for physicians at
this link
(make sure you read that disclaimer there). Mind you, I'm anything but a renal
specialist. But having the tables handy might facilitate your discussions with
her doctors. Notice that one of the variables is how your wife's
kidneys are functioning. The tables in Aranoff's book are set up based on
that. So that will be an important thing to know about. Note also that they're
talking about kidney function, not dialysis, in terms of how doses need to be
changed. But that will be an important variable to be understood, as well as
what the dialysis process does to medication levels. Good luck with that.
Dr. Phelps
Published January, 2005
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